FIGURE

Fig. 6

ID

ZDB-FIG-060809-15

Publication

Nissen et al., 2006 - A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for Endothelin-1 expression

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Fig. 6

Transformation of 2^ndarch identity transforms 2^ndarch wdr68 sensitivity. A, C) Lateral views at 4dpf. B, D) Ventral views at 4dpf. A, B) Wild type animal injected with mozMO transforms 2^ndarch cartilage elements into mirror image duplicates of 1^starch cartilages. C, D) Injecting dys animals with mozMO reveals similar cartilage losses as in maternal wdr68 knockdowns shown in (Fig. 4E, F) but with further reduction of HM region presumably through mirror image duplication of the missing 1^starch cartilages.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-kat6a dcaf7^{hi3812Tg/hi3812Tg} + MO3-kat6a
Knockdown Reagent:	MO3-kat6a
Observed In:	cartilage development ceratohyal cartilage mandibular arch skeleton Meckel's cartilage palatoquadrate cartilage pharyngeal arch 2 skeleton
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.