FIGURE

Fig. 5

ID

ZDB-FIG-050609-7

Publication

Oates et al., 2005 - Cooperative function of deltaC and her7 in anterior segment formation

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Fig. 5

Analysis of the interaction between deltaC and the after eight/deltaD (aei/dld), beamter (bea), and deadly seven/notch1a (des/n1a) mutations in the Delta/Notch signaling pathway. Myotome boundaries in the trunk are shown in 26 hpf embryos in lateral view with anterior to the left and dorsal upwards (A–C, E–G, I–K). (A) aei/dld uninjected, (B) wild type injected with 1 ng/nL dlcMO3 and 1 ng/nL dlcMO4, (C) aei/dld injected with dlcMOs. (E) bea uninjected, (F) bea injected with 1 ng/nL dlcMO3 and 2 ng/nL dlcMO4, (G) bea injected with 3 ng/nL her7MO1 and 3 ng/nL her7MO2. (I) des/n1a uninjected, (J) wild type injected with 0.5 ng/nL dlcMO3 and 0.5 ng/nL dlcMO4. (D, H, L) Histograms comparing Anterior Limit of Defects (ALD) for these nine conditions. Arrows in panel (A–C), (E–G), and (I–K) indicate ALD in each embryo.

Expression Data

Gene:	ttn.2
Fish:	dlc^tm98/tm98 dlc^tm98/tm98 + MO3-dlc + MO4-dlc dld^tr233/tr233 notch1a^tp37/tp37 WT + MO3-dlc + MO4-dlc dlc^tm98/tm98 + MO1-her7 + MO2-her7 dld^tr233/tr233 + MO3-dlc + MO4-dlc notch1a^tp37/tp37 + MO3-dlc + MO4-dlc
Knockdown Reagents:	MO1-her7 MO2-her7 MO3-dlc MO4-dlc
Anatomical Term:	myotome
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 280(1), Oates, A.C., Mueller, C., and Ho, R.K., Cooperative function of deltaC and her7 in anterior segment formation, 133-149, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.