ZFIN All Figures, Armistead <i>et al.</i>, 2020

Fig. 1

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	mmp9 spint1a
Fish:	spint1a^fr26/fr26 spint1a^{hi2217Tg/hi2217Tg}
Anatomical Term:	caudal fin
Stage:	Long-pec

Expression / Labeling details

PHENOTYPE:

Fish:	spint1a^fr26/fr26 spint1a^{hi2217Tg/hi2217Tg} spint1a^fr26/fr26 + MO1-st14a
Knockdown Reagent:	MO1-st14a
Observed In:	caudal fin caudal fin cell population proliferation caudal fin epidermal cell whole organism
Stage Range:	1-cell to Days 7-13

Phenotype details

Fig. 2

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Antibodies:	Ab1-rps6 Ab4-egfr
Fish:	WT spint1a^{hi2217Tg/hi2217Tg} spint1a^{hi2217Tg/hi2217Tg} + MO2-f2rl1.2
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: PD 168393 chemical treatment by environment: sirolimus
Knockdown Reagent:	MO2-f2rl1.2
Anatomical Term:	caudal fin
Stage:	Long-pec

Expression / Labeling details

PHENOTYPE:

Fish:	spint1a^{hi2217Tg/hi2217Tg} spint1a^{hi2217Tg/hi2217Tg} + MO2-f2rl1.2
Conditions:	chemical treatment by environment: butan-1-ol chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: PD 168393 chemical treatment by environment: sirolimus
Knockdown Reagent:	MO2-f2rl1.2
Observed In:	caudal fin caudal fin cell population proliferation caudal fin epidermal cell
Stage:	Long-pec

Phenotype details

Fig. 3

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Genes:	DsRed GFP
Fish:	fr46Tg; gz7Tg spint1a^{hi2217Tg/hi2217Tg}; fr46Tg; gz7Tg
Anatomical Terms:	keratinocyte peridermal cell
Stage:	Long-pec

Expression / Labeling details

PHENOTYPE:

Fish:	spint1a^{hi2217Tg/hi2217Tg}; fr46Tg; gz7Tg
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: PD 168393 chemical treatment by environment: sirolimus
Observed In:	epidermal basal stratum cell epidermis peridermal cell
Stage:	Long-pec

Phenotype details

Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:

Gene:	mmp9
Antibody:	Ab1-lama1
Fish:	WT spint1a^{hi2217Tg/hi2217Tg} spint1a^{hi2217Tg/hi2217Tg} + MO2-f2rl1.2
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: PD 168393 chemical treatment by environment: sirolimus
Knockdown Reagent:	MO2-f2rl1.2
Anatomical Terms:	caudal fin caudal fin epidermal basal stratum
Stage:	Long-pec

Expression / Labeling details

PHENOTYPE:

Fish:	spint1a^{hi2217Tg/hi2217Tg} WT + MO1-spint1a spint1a^{hi2217Tg/hi2217Tg} + MO2-f2rl1.2 WT + MO1-spint1a + MO1-st14a WT + MO1-spint1a + MO2-itga3b WT + MO1-spint1a + MO3-lama5 WT + MO1-spint1a + MO1-st14a + MO2-itga3b WT + MO1-spint1a + MO1-st14a + MO3-lama5
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: PD 168393 chemical treatment by environment: sirolimus
Knockdown Reagents:	MO1-spint1a MO1-st14a MO2-f2rl1.2 MO2-itga3b MO3-lama5
Observed In:	caudal fin caudal fin epidermal basal stratum caudal fin epidermal cell epidermal basal stratum cell epidermis peridermal cell
Stage:	Long-pec

Phenotype details

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	s1pr2^te273/te273 spint1a^{hi2217Tg/hi2217Tg} s1pr2^te273/te273; spint1a^{hi2217Tg/hi2217Tg}
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: EC 2.7.1.91 (sphingosine kinase) inhibitor
Observed In:	caudal fin cell population proliferation caudal fin epidermal cell epidermal basal stratum cell epidermis keratinocyte cell population proliferation peridermal cell
Stage Range:	Long-pec to Day 4

Phenotype details

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

PHENOTYPE:

Fish:	spint1a^fr26/fr26
Conditions:	chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor chemical treatment by environment: sphingosine 1-phosphate
Observed In:	caudal fin cell population proliferation caudal fin epidermal cell epidermal basal stratum cell epidermis peridermal cell whole organism
Stage Range:	Long-pec to Days 7-13

Phenotype details

Acknowledgments

Full text @ J. Cell Biol.

Armistead et al., 2020

ZDB-PUB-191212-23
PMID:31819976

Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase

Armistead et al., 2020 ZDB-PUB-191212-23 PMID:31819976

Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase

Armistead et al., 2020

ZDB-PUB-191212-23
PMID:31819976