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Phenotype Figure Summary
Marker:
myo1d
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Kurup
et al.
, 2024
Fig. 1
myo1d
nce16c/nce16c
, 
myo1d
nce16b/nce16b
brain left/right pattern formation decreased process quality, abnormal
epithalamus dorsal side
pitx2
expression decreased amount, abnormal
epithalamus dorsal side
pitx2
expression spatial pattern, abnormal
gut
foxa1
expression spatial pattern, abnormal
gut left/right pattern formation decreased process quality, abnormal
heart jogging decreased process quality, abnormal
liver
foxa1
expression spatial pattern, abnormal
pancreas
foxa1
expression spatial pattern, abnormal
pancreas left/right pattern formation decreased process quality, abnormal
Fig. 2
myo1d
nce16c/nce16c
lateral plate mesoderm left side
spaw
expression spatial pattern, abnormal
Juan
et al.
, 2018
Fig. 1
myo1d
nce16c/nce16c
, 
myo1d
nce16b/nce16b
determination of heart left/right asymmetry decreased process quality, abnormal
determination of liver left/right asymmetry process quality, abnormal
determination of pancreatic left/right asymmetry process quality, abnormal
gut determination of digestive tract left/right asymmetry process quality, abnormal
heart heart looping decreased process quality, abnormal
heart mislocalised, abnormal
heart tube heart jogging decreased process quality, abnormal
heart tube mislocalised, abnormal
Fig. 2
myo1d
nce16b/nce16b
Kupffer's vesicle
dand5
expression spatial pattern, abnormal
Fig. 3
myo1d
nce16b/nce16b
Kupffer's vesicle decreased area, abnormal
Fig. 4
myo1d
nce16c/nce16c
Kupffer's vesicle epithelial cilium movement involved in determination of left/right asymmetry process quality, abnormal
Fig. 5
myo1d
nce16c/nce16c
Kupffer's vesicle cilium decreased size, abnormal
Kupffer's vesicle decreased area, abnormal
Fig. 6
myo1d
nce16b/nce16b
Kupffer's vesicle ciliary basal body mislocalised anteriorly, abnormal
Kupffer's vesicle cilium posterior orientation, abnormal
Fig. S2
myo1d
nce16b/nce16b
determination of left/right asymmetry in nervous system process quality, abnormal
Saydmohammed
et al.
, 2018
Fig. 1
myo1d
pt31a/pt31a
, 
myo1d
pt31a/pt31a
; pt21Tg
Kupffer's vesicle decreased area, abnormal
Kupffer's vesicle development decreased process quality, abnormal
Kupffer's vesicle elliptic, abnormal
Kupffer's vesicle malformed, abnormal
otic vesicle decreased area, abnormal
otic vesicle development decreased process quality, abnormal
otic vesicle malformed, abnormal
Fig. 2
myo1d
pt31a/pt31a
gut determination of digestive tract left/right asymmetry decreased occurrence, abnormal
heart heart looping decreased occurrence, abnormal
Kupffer's vesicle
dand5
expression spatial pattern, abnormal
Kupffer's vesicle epithelial cilium movement involved in determination of left/right asymmetry physical quality of a process, abnormal
lateral plate mesoderm right side
spaw
expression mislocalised, abnormal
Fig. 3
myo1d
pt31a/pt31a
; pt21Tg
, 
pt21Tg + MO1-myo1d
Kupffer's vesicle epithelial cell columnar, abnormal
Kupffer's vesicle epithelial cell morphogenesis process quality, abnormal
Kupffer's vesicle posterior region has extra parts of type Kupffer's vesicle vacuole, abnormal
Kupffer's vesicle vacuolar transport decreased rate, abnormal
Kupffer's vesicle vacuole increased volume, abnormal
Fig. 4
myo1d
pt31a/pt31a
; pt21Tg
Kupffer's vesicle nucleus broken, abnormal
Fig. 5
myo1d
pt31a/pt31a
; pt21Tg
heart heart looping decreased occurrence, abnormal
Kupffer's vesicle decreased area, abnormal
Kupffer's vesicle development decreased process quality, abnormal
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