TALEN

TALEN1-dusp6

ID

ZDB-TALEN-180725-1

Name

TALEN1-dusp6

Previous Names

None

Target

dusp6 (1)

Target Sequence 1

5' - TCGATAAGTTCAAACCC - 3'

Target Sequence 2

5' - TCTTGCTTATGGCCAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
pt30a	dusp6
pt30b	dusp6
pt30c	dusp6
pt30d	dusp6

Expression

Gene expression in Wild Types + TALEN1-dusp6

No data available

Phenotype

Phenotype resulting from TALEN1-dusp6

No data available

Phenotype of all Fish created by or utilizing TALEN1-dusp6

Phenotype	Fish	Conditions	Figures
heart structure, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 , Fig. S11 from Missinato et al., 2018
cardiac muscle cell increased amount, abnormal	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 3 from Missinato et al., 2018
heart fn1b expression amount, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
compact layer of ventricle increased thickness, abnormal	dusp6^pt30a/pt30a	standard conditions	Fig. 2 from Missinato et al., 2018
cardiac ventricle cardiac muscle cell proliferation increased process quality, abnormal	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 3. from Zuppo et al., 2023
heart contraction rhythm quality, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
whole organism dusp6 expression absent, abnormal	dusp6^pt30a/pt30a	standard conditions	Fig. 2 from Missinato et al., 2018
heart structure, ameliorated	dusp6^pt30a/pt30a	chemical treatment by injection: PDGF receptor tyrosine kinase inhibitor III, resection: cardiac ventricle	Fig. 6 from Missinato et al., 2018
cardiac muscle cell proliferation increased process quality, abnormal	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 3 , Fig. 7 from Missinato et al., 2018
cardiac muscle tissue regeneration increased rate, abnormal	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
heart structure, ameliorated	dusp6^pt30a/pt30a	chemical treatment by injection: tyrphostin AG 1478, resection: cardiac ventricle	Fig. S11 from Missinato et al., 2018
heart errfi1b expression increased amount, abnormal	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 7 from Missinato et al., 2018
heart col12a1a expression amount, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
heart increased size, abnormal	dusp6^pt30a/pt30a	standard conditions	Fig. 2 from Missinato et al., 2018
heart cybb expression amount, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
heart postna expression amount, ameliorated	dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 4 from Missinato et al., 2018
cardiac muscle cell proliferation increased process quality, abnormal	dusp6^pt30d/pt30d	resection: cardiac ventricle	Fig. S4 from Missinato et al., 2018
compact layer of ventricle increased thickness, abnormal	dusp6^pt30a/pt30a; y1Tg	standard conditions	Fig. 2 from Missinato et al., 2018
cardiac muscle tissue regeneration increased rate, abnormal	dusp6^pt30a/pt30a; y1Tg	resection: cardiac ventricle	Fig. 3 from Missinato et al., 2018
regenerating tissue angiogenesis increased process quality, abnormal	dusp6^pt30a/pt30a; y1Tg	resection: cardiac ventricle	Fig. 3 from Missinato et al., 2018
compact layer of ventricle blood vessel increased amount, abnormal	dusp6^pt30a/pt30a; y1Tg	standard conditions	Fig. 2 from Missinato et al., 2018
compact layer of ventricle blood vessel ab2-mapk labeling increased amount, abnormal	dusp6^pt30a/pt30a; y1Tg	standard conditions	Fig. 2 from Missinato et al., 2018
cardiac ventricle cardiac muscle cell proliferation decreased process quality, abnormal	foxm1^{sa10708/sa10708}; dusp6^pt30a/pt30a	resection: cardiac ventricle	Fig. 3. from Zuppo et al., 2023

Citations