TALEN

TALEN2-rb1

ID

ZDB-TALEN-170929-1

Name

TALEN2-rb1

Previous Names

None

Target

rb1 (1)

Target Sequence 1

5' - CCAGTCCACTAACTCCAT - 3'

Target Sequence 2

5' - TCTCCCTCTCCCATATTCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Targets exon 2

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
is54	rb1

Expression

Gene expression in Wild Types + TALEN2-rb1

No data available

Phenotype

Phenotype resulting from TALEN2-rb1

Phenotype	Fish	Figures
brain morphology, abnormal	WIK + TALEN2-rb1	Fig. 1 from Solin et al., 2015
brain cell population proliferation increased occurrence, abnormal	WIK + TALEN2-rb1	Fig. S2 from Solin et al., 2015
brain neoplasm increased amount, abnormal	WIK + TALEN2-rb1	Fig. 2 from Solin et al., 2015
head malformed, abnormal	WIK + TALEN2-rb1	Fig. 1 from Solin et al., 2015
swimming behavior disrupted, abnormal	WIK + TALEN2-rb1	Fig. 1 from Solin et al., 2015

Phenotype of all Fish created by or utilizing TALEN2-rb1

Phenotype	Fish	Conditions	Figures
head rbbp4 expression increased amount, abnormal	rb1^is54/is54	control	Fig. 4 from Schultz et al., 2018
brain cell population proliferation increased occurrence, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
optic tectum ab18-h3 labeling increased distribution, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
retinal inner nuclear layer ab18-h3 labeling increased distribution, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
retinal inner nuclear layer ab18-h3 labeling mislocalised, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
retinal outer nuclear layer ab18-h3 labeling mislocalised, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
retina cell population proliferation increased occurrence, abnormal	rb1^is54/is54	control	Fig. 7 from Schultz-Rogers et al., 2022 Fig. 2 from Schultz et al., 2018
thalamus ab18-h3 labeling mislocalised, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
thalamus ab18-h3 labeling increased distribution, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
midbrain cell population proliferation increased occurrence, abnormal	rb1^is54/is54	standard conditions	Fig. 7 from Schultz-Rogers et al., 2022
optic tectum ab18-h3 labeling mislocalised, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
head ascl1b expression increased amount, abnormal	rb1^is54/is54	control	Fig. 4 from Schultz et al., 2018
head hdac1 expression increased amount, abnormal	rb1^is54/is54	control	Fig. 4 from Schultz et al., 2018
retinal outer nuclear layer ab18-h3 labeling increased distribution, abnormal	rb1^is54/is54	control	Fig. 2 from Schultz et al., 2018
head olig2 expression increased amount, abnormal	rb1^is54/is54	control	Fig. 4 from Schultz et al., 2018
brain neoplasm increased amount, abnormal	WIK + TALEN2-rb1	standard conditions	Fig. 2 from Solin et al., 2015
brain morphology, abnormal	WIK + TALEN2-rb1	standard conditions	Fig. 1 from Solin et al., 2015
swimming behavior disrupted, abnormal	WIK + TALEN2-rb1	standard conditions	Fig. 1 from Solin et al., 2015
head malformed, abnormal	WIK + TALEN2-rb1	standard conditions	Fig. 1 from Solin et al., 2015
brain cell population proliferation increased occurrence, abnormal	WIK + TALEN2-rb1	standard conditions	Fig. S2 from Solin et al., 2015
retina cell population proliferation increased occurrence, exacerbated	rb1^is54/is54; rbbp4^is60/is60	standard conditions	Fig. 7 from Schultz-Rogers et al., 2022
retina apoptotic, abnormal	rb1^is54/is54; rbbp4^is60/is60	standard conditions	Fig. 8 from Schultz-Rogers et al., 2022
midbrain cell population proliferation increased occurrence, exacerbated	rb1^is54/is54; rbbp4^is60/is60	standard conditions	Fig. 7 from Schultz-Rogers et al., 2022

Citations