Morpholino

MO1-prdm12b

ID

ZDB-MRPHLNO-140710-5

Name

MO1-prdm12b

Previous Names

None

Target

Sequence

5' - GCAGGCAACACTGAACCCATGATGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-prdm12b

Expressed Gene	Anatomy	Figures
alcama	facial nerve motor nucleus	Fig. 6 from Zannino et al., 2014
dbx1a	hindbrain dorso-medial region	Fig. 5 from Zannino et al., 2014
en1b	(not) CiA midbrain hindbrain boundary (not) MiV1 muscle pioneer rhombomere 4 somite	Fig. 7 from Yildiz et al., 2019 Fig. 3 from Zannino et al., 2014
evx1	hindbrain lateral region spinal cord interneuron	Fig. 3 , Fig. 5 from Zannino et al., 2014
irx3a	hindbrain dorso-medial region	Fig. 5 from Zannino et al., 2014
nkx2.2a	hindbrain ventro-medial region spinal cord interneuron	Fig. 3 , Fig. 5 from Zannino et al., 2014
nkx6.1	hindbrain ventro-medial region	Fig. 5 from Zannino et al., 2014
olig2	hindbrain ventro-medial region spinal cord central region	Fig. 5 , Fig. 6 , Fig. 7 from Zannino et al., 2014
pax3a	hindbrain dorsal region	Fig. 5 from Zannino et al., 2014
plp1a	hindbrain oligodendrocyte	Fig. 7 from Zannino et al., 2014
sox10	hindbrain glioblast (sensu Vertebrata)	Fig. 7 from Zannino et al., 2014
vsx2	hindbrain ventro-lateral region spinal cord interneuron	Fig. 3 , Fig. 5 , Fig. 7 from Zannino et al., 2014

Phenotype

Phenotype resulting from MO1-prdm12b

Phenotype	Fish	Figures
abducens motor nucleus has fewer parts of type abducens motor nucleus motor neuron, abnormal	WT + MO1-prdm12b	Fig. 6 from Zannino et al., 2014
facial nerve motor nucleus motor neuron mislocalised, abnormal	um8Tg + MO1-prdm12b	Fig. 6 from Zannino et al., 2014
hindbrain has fewer parts of type glioblast (sensu Vertebrata), abnormal	vu12Tg + MO1-prdm12b	Fig. 8 from Zannino et al., 2014
hindbrain has fewer parts of type oligodendrocyte, abnormal	WT + MO1-prdm12b	Fig. 7 from Zannino et al., 2014
hindbrain interneuron neuron fate specification process quality, abnormal	WT + MO1-prdm12b	Fig. 5 from Zannino et al., 2014
oligodendrocyte progenitor proliferation increased occurrence, abnormal	vu12Tg + MO1-prdm12b	Fig. 8 from Zannino et al., 2014
spinal cord lacks all parts of type CiA, abnormal	WT + MO1-prdm12b	Fig. 3 from Zannino et al., 2014
spinal cord ventral region decreased size, abnormal	WT + MO1-prdm12b	Fig. 8 from Yildiz et al., 2019
thigmotaxis increased duration, abnormal	WT + MO1-prdm12b	Fig. 9 from Zannino et al., 2014
thigmotaxis increased magnitude, abnormal	WT + MO1-prdm12b	Fig. 9 from Zannino et al., 2014
ventral spinal cord interneuron specification decreased process quality, abnormal	WT + MO1-prdm12b	Fig. 3 from Zannino et al., 2014

Phenotype of all Fish created by or utilizing MO1-prdm12b

Phenotype	Fish	Conditions	Figures
hindbrain interneuron neuron fate specification process quality, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 5 from Zannino et al., 2014
ventral spinal cord interneuron specification decreased process quality, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 3 from Zannino et al., 2014
thigmotaxis increased magnitude, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 9 from Zannino et al., 2014
thigmotaxis increased duration, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 9 from Zannino et al., 2014
hindbrain has fewer parts of type oligodendrocyte, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 7 from Zannino et al., 2014
abducens motor nucleus has fewer parts of type abducens motor nucleus motor neuron, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 6 from Zannino et al., 2014
spinal cord ventral region decreased size, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 8 from Yildiz et al., 2019
spinal cord lacks all parts of type CiA, abnormal	WT + MO1-prdm12b	standard conditions	Fig. 3 from Zannino et al., 2014
facial nerve motor nucleus motor neuron mislocalised, abnormal	um8Tg + MO1-prdm12b	standard conditions	Fig. 6 from Zannino et al., 2014
hindbrain has fewer parts of type glioblast (sensu Vertebrata), abnormal	vu12Tg + MO1-prdm12b	standard conditions	Fig. 8 from Zannino et al., 2014
oligodendrocyte progenitor proliferation increased occurrence, abnormal	vu12Tg + MO1-prdm12b	standard conditions	Fig. 8 from Zannino et al., 2014

Citations