Morpholino

MO3-nipblb

ID
ZDB-MRPHLNO-131219-3
Name
MO3-nipblb
Previous Names
None
Target
Sequence
5' - GTCCCCATTCATGCTGAAGAAGGGA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-nipblb
Expressed Gene Anatomy Figures
axin2 Fig. 3 from Mazzola et al., 2019
Fig. 4 from Pistocchi et al., 2013
ccnd1 Fig. 6 from Fazio et al., 2016
Fig. 5 from Pistocchi et al., 2013
gata1a FIGURE 3 with image from Mazzola et al., 2020
runx1 FIGURE 2 with image from Mazzola et al., 2020
spi1b FIGURE 3 with image from Mazzola et al., 2020
Fig. 5 from Mazzola et al., 2019
wnt1 Fig. 4 from Pistocchi et al., 2013
Phenotype
Phenotype resulting from MO3-nipblb
Phenotype Fish Figures
apoptotic process increased occurrence, abnormal AB + MO3-nipblb Fig. 3 from Pistocchi et al., 2013
brain decreased size, abnormal AB + MO3-nipblb Fig. 2 from Pistocchi et al., 2013
caudal hematopoietic tissue GFP expression increased amount, abnormal w25Tg + MO3-nipblb Fig. 3 from Mazzola et al., 2019
caudal hematopoietic tissue spi1b expression increased amount, abnormal AB + MO3-nipblb Fig. 5 from Mazzola et al., 2019
caudal hematopoietic tissue canonical Wnt signaling pathway increased occurrence, abnormal w25Tg + MO3-nipblb Fig. 3 from Mazzola et al., 2019
caudal hematopoietic tissue common myeloid progenitor increased amount, abnormal AB + MO3-nipblb Fig. 2,  Fig. 5 from Mazzola et al., 2019
caudal hematopoietic tissue neutrophil decreased amount, abnormal AB + MO3-nipblb Fig. 2 from Mazzola et al., 2019
cell population proliferation disrupted, abnormal AB + MO3-nipblb Fig. 4 from Fazio et al., 2016
central nervous system development disrupted, abnormal AB + MO3-nipblb Fig. 5 from Pistocchi et al., 2013
eye decreased size, abnormal AB + MO3-nipblb Fig. 2 from Pistocchi et al., 2013
hematopoietic stem cell canonical Wnt signaling pathway increased occurrence, abnormal la2Tg + MO3-nipblb Fig. 4 from Mazzola et al., 2019
neural tube apoptotic, abnormal AB + MO3-nipblb Fig. 3 from Pistocchi et al., 2013
neural tube apoptotic process increased occurrence, abnormal AB + MO3-nipblb Fig. 4 from Fazio et al., 2016
nucleate erythrocyte decreased amount, abnormal AB + MO3-nipblb FIGURE 3 with image from Mazzola et al., 2020
post-vent region curved, abnormal AB + MO3-nipblb Fig. 2 from Pistocchi et al., 2013
post-vent region decreased length, abnormal AB + MO3-nipblb Fig. 2 from Pistocchi et al., 2013
regulation of canonical Wnt signaling pathway disrupted, abnormal AB + MO3-nipblb Fig. 5 from Pistocchi et al., 2013
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal AB + MO3-nipblb FIGURE 2 with image from Mazzola et al., 2020
whole organism gata1a expression decreased amount, abnormal AB + MO3-nipblb FIGURE 3 with image from Mazzola et al., 2020
whole organism ccnd1 expression decreased amount, abnormal AB + MO3-nipblb Fig. 6 from Fazio et al., 2016
whole organism spi1b expression increased amount, abnormal AB + MO3-nipblb FIGURE 3 with image from Mazzola et al., 2020
whole organism axin2 expression increased amount, abnormal AB + MO3-nipblb Fig. 3 from Mazzola et al., 2019
Phenotype of all Fish created by or utilizing MO3-nipblb
Phenotype Fish Conditions Figures
whole organism spi1b expression increased amount, abnormal AB + MO3-nipblb standard conditions FIGURE 3 with image from Mazzola et al., 2020
caudal hematopoietic tissue spi1b expression increased amount, abnormal AB + MO3-nipblb control Fig. 5 from Mazzola et al., 2019
neural tube apoptotic, abnormal AB + MO3-nipblb standard conditions Fig. 3 from Pistocchi et al., 2013
central nervous system development disrupted, abnormal AB + MO3-nipblb standard conditions Fig. 5 from Pistocchi et al., 2013
nucleate erythrocyte decreased amount, abnormal AB + MO3-nipblb standard conditions FIGURE 3 with image from Mazzola et al., 2020
caudal hematopoietic tissue neutrophil decreased amount, abnormal AB + MO3-nipblb control Fig. 2 from Mazzola et al., 2019
regulation of canonical Wnt signaling pathway disrupted, abnormal AB + MO3-nipblb standard conditions Fig. 5 from Pistocchi et al., 2013
post-vent region decreased length, abnormal AB + MO3-nipblb standard conditions Fig. 2 from Pistocchi et al., 2013
brain decreased size, abnormal AB + MO3-nipblb standard conditions Fig. 2 from Pistocchi et al., 2013
post-vent region curved, abnormal AB + MO3-nipblb standard conditions Fig. 2 from Pistocchi et al., 2013
caudal hematopoietic tissue common myeloid progenitor increased amount, abnormal AB + MO3-nipblb control Fig. 2,  Fig. 5 from Mazzola et al., 2019
whole organism gata1a expression decreased amount, abnormal AB + MO3-nipblb standard conditions FIGURE 3 with image from Mazzola et al., 2020
caudal hematopoietic tissue common myeloid progenitor amount, ameliorated AB + MO3-nipblb chemical treatment by environment: indometacin Fig. 5 from Mazzola et al., 2019
neural tube apoptotic process increased occurrence, abnormal AB + MO3-nipblb standard conditions Fig. 4 from Fazio et al., 2016
apoptotic process increased occurrence, abnormal AB + MO3-nipblb standard conditions Fig. 3 from Pistocchi et al., 2013
whole organism ccnd1 expression decreased amount, abnormal AB + MO3-nipblb standard conditions Fig. 6 from Fazio et al., 2016
whole organism axin2 expression increased amount, abnormal AB + MO3-nipblb control Fig. 3 from Mazzola et al., 2019
ventral wall of dorsal aorta runx1 expression decreased amount, abnormal AB + MO3-nipblb standard conditions FIGURE 2 with image from Mazzola et al., 2020
eye decreased size, abnormal AB + MO3-nipblb standard conditions Fig. 2 from Pistocchi et al., 2013
caudal hematopoietic tissue spi1b expression amount, ameliorated AB + MO3-nipblb chemical treatment by environment: indometacin Fig. 5 from Mazzola et al., 2019
cell population proliferation disrupted, abnormal AB + MO3-nipblb standard conditions Fig. 4 from Fazio et al., 2016
caudal hematopoietic tissue common myeloid progenitor increased amount, abnormal la2Tg + MO3-nipblb control Fig. 2 from Mazzola et al., 2019
hematopoietic stem cell canonical Wnt signaling pathway increased occurrence, abnormal la2Tg + MO3-nipblb control Fig. 4 from Mazzola et al., 2019
caudal hematopoietic tissue canonical Wnt signaling pathway increased occurrence, abnormal w25Tg + MO3-nipblb control Fig. 3 from Mazzola et al., 2019
caudal hematopoietic tissue GFP expression increased amount, abnormal w25Tg + MO3-nipblb control Fig. 3 from Mazzola et al., 2019
developmental growth arrested, abnormal AB + MO1-smc1a + MO3-nipblb standard conditions Fig. 6 from Fazio et al., 2016
embryo development delayed, abnormal AB + MO1-smc1a + MO3-nipblb standard conditions Fig. 6 from Fazio et al., 2016
whole organism dead, abnormal AB + MO1-smc1a + MO3-nipblb standard conditions Fig. 6 from Fazio et al., 2016
whole organism ccnd1 expression decreased amount, abnormal WT + MO1-smc1a + MO3-nipblb standard conditions Fig. 6 from Fazio et al., 2016
Citations
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