IMAGE

Figure 7

ID

ZDB-IMAGE-200725-26

Genes

ush2a

Antibodies

Ab2-ush2a

Source

Figures for Toms et al., 2020

Image

Figure Caption

Figure 7

Auditory function in ush2a^u507 larvae. (A) and (B) Macular hair cell cross-sections from 6 days post fertilization (dpf) wt and ush2a^u507 larvae were immunostained with anti-acetylated tubulin (red), anti-usherin-N (green) and DAPI (blue). (C) and (D) Stereociliary hair bundles of the anterior macula in wt and ush2a^u507 zebrafish at 6 days post fertilization stained with Alexa Fluor 647 Phalloidin. Bar graph (E) shows the number of hair cell bundles per anterior macula in wt and ush2a^u507 larvae (mean ± SEM, n = 10). Bar graph (F) shows distance moved in response to acoustic stimuli of different frequencies (mean ± SEM, n ≥ 77 from three biological replicates per group). An unpaired t-test or two-way ANOVA were used to test for statistical significance. ^*P < 0.05. Scale bars = 10 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Hum. Mol. Genet.