ZFIN Image: Tomecka et al., 2019, Fig. 6.

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Figure Caption

Fig. 6.

Genetic ablation of osteoclasts reduces bone callus resorption. (A,B) TRAP staining of fractures in WT (A) and csf1ra^j4e1 mutants (B) at given time points following crush. (C) The area of TRAP staining was significantly reduced in the mutants at all time points (n=12). (D,E) Fluorescent images of WT (D) and csf1ra^j4e1 mutant (E) fractures stained with calcein. The time points following crush are given. (F) Relative callus width measurements at different time points for fractures of WT and csf1ra mutants at given time points (n=15). By 42 hpc, the mutants had significantly fewer remodelled calluses. *P<0.05, **P<0.01, ***P<0.001; ANOVA with Sidak post test. Scale bars: in B and D, 100 µm for A,B,D,E.

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Acknowledgments

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