IMAGE

Fig. S5

ID
ZDB-IMAGE-180823-47
Genes
Source
Figures for Ghosh et al., 2018
Image
Figure Caption

Fig. S5 SU5402 disrupts embryogenesis in hoxb1b mutants. Wildtype (i) and hoxb1b mutant (ii) zebrafish embryos were treated with SU5402 and assayed at various developmental stages by brightfield microscopy (A, B, F, H), or ISH to detect expression of efnb2a/krox20 (C), meis1a/krox20 (D), irx7/krox20 (E) or greb1l/krox20 (G). Note that defects in development are readily detectable in hoxb1b mutants treated with 50uM SU5402 (Aii, Bii), but not in WT embryos treated with SU5402 (Ai, Bi), nor in hoxb1b mutants treated with DEAB (Biii). As a result of these severe developmental defects, hoxb1b mutant embryos treated with SU5402 showed no specific staining for the r4 genes tested. (PDF 853 kb)

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Neural Dev.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.