Gene

irx7

ID
ZDB-GENE-020103-1
Name
iroquois homeobox 7
Symbol
irx7 Nomenclature History
Previous Names
  • iro7
  • cb263 (1)
  • zgc:109841
  • ziro7 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in several processes, including embryonic skeletal joint development; nervous system development; and retina morphogenesis in camera-type eye. Predicted to localize to nucleus. Is expressed in several structures, including head; interhyal-hyosymplectic joint; nervous system; neural keel; and neural plate.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
30 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With irx7 Human Ortholog
No data available
Associated With irx7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR003893 Iroquois-class homeodomain protein
Domain IPR008422 KN homeodomain
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain Iroquois-class homeodomain protein KN homeodomain
UniProtKB:Q90YX8 314
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA irx7-201 (1) Ensembl 1,187 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-irx7 polyclonal Rabbit
  • WB
1
Ab2-irx7 polyclonal Rabbit
  • WB
1
Ab3-irx7 polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations