ZFIN Image: Rosenfeld et al., 2013, Fig. 6

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Figure Caption

Fig. 6

Hspb7 is required for establishment of left–right asymmetry. (A–C) Representative in situ hybridization expression patterns of the left–right asymmetry markers lft1 (A), lft2 (B), or spaw (C). Panels in (A) and (B) show, left to right, normal (leftward), bilateral, or right-sided expression in embryos at the 22-somite stage. Panels in (C) are likewise, but the embryos are at the 18 somite stage, and some hspb7 morphants show a partial pattern of bilateral expression (far right panel). All views are dorsal, with anterior to the top. (D–F) Quantification of these phenotypes, and in each case n is at least 18 embryos.

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Acknowledgments

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Reprinted from Developmental Biology, 381(2), Rosenfeld, G.E., Mercer, E.J., Mason, C.E., and Evans, T., Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis, 389-400, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.