ZFIN Image: Wang et al., 2013, Fig. 7

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Figure Caption

Fig. 7 Notch signaling was not activated in the AVC of sco^te382 mutant hearts. (A–F) Tg(Tp1bglob:hmgb1-mCherry)^jh11, called Tg(Tp1:mCherry), transgenic zebrafish (Parsons et al., 2009) were bred with sco^te382/te382; Tg(kdrl:eGFP) transgenic zebrafish to generate sco^te382/+; Tg(Tp1:mCherry)/+; Tg(kdrl:eGFP)/+ zebrafish. Images were taken with agarose-embedded embryos using Zeiss 700 upright confocal microscope. Endocardial cells labeled by Tg(kdrl:eGFP) were used to project the heart shapes. Note that Tg(Tp1:mCherry) were gradually restricted in the AVC of wild-type hearts at 48hpf (A), 60hpf (C) to 72hpf (E), but were ectopically expressed in the ventricle of sco^te382 mutant hearts at 48hpf (B), 60hpf (D) and 72hpf (F). a, atrium; v, ventricle. Red arrowheads point to the AVC.

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Acknowledgments

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