ZFIN Image: Smith et al., 2011, Fig. 3

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Figure Caption

Fig. 3

Dose-dependent effect of Bmpr1a on the expression of laterality genes.

In situ hybridisation at 18-somites for spaw (in LPM) and no tail (ntl) (in midline) (A–C), lefty1 at 23-somites (heart field and midline) (D–F) and pitx2 at 23-somites (in LPM) (G–I). (A,D,G) Embryos selected for normal ventral tail fin or C1 dorsalization (genotypes: bmpr1aa +/+ or +/- bmpr1ab +/+ or +/- or -/-). (B,E,H) Embryos selected for C3 dorsalization (genotype bmpr1aa-/-;bmp1ab+/-). (C,F,I) Embryos selected for C4 dorsalization (genotype bmpr1aa-/-;bmpr1ab-/-). All embryos are shown as dorsal views with anterior to the top and left to the left. Number of embryos examined is presented in Table 2.

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Acknowledgments

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