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Fig. S2
Early and late Schwann cell markers are absent in nrg1z26 mutants. (A,B) Dorsal views of nrg1 type III mRNA expression in nrg1z26/+ (A) and nrg1z26 (n=3/3) embryos at 35 hpf. Arrow marks PLLg. (C,D) sox10 marks Schwann cells along the PLLn (arrowheads) in a wild-type embryo (C), but is almost absent along the PLLn of an nrg1z26 mutant (n=11/11) (D). (E-H) Myelin basic protein mRNA (E) and protein (G) is expressed along the PLLn (arrowheads) of wild-type embryos, but not in nrg1z26 mutants (F, n=3/3; H, n=6/6). Scale bar: 50 μm.
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