ZFIN Image: Dal-Pra et al., 2011, Fig. S1

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Figure Caption

Fig. S1 Abnormal development of the axial structures remaining in partial FoxA2–FoxA3 morphants. Expression of notochord (im:7144261) (A–C) and floor plate markers (foxA2) (D–F) at 24 hpf. (A and B) Transverse sections showing that the notochord is smaller in FoxA2–FoxA3 morphants compared to wild-type, and that some of these cells are mislocated in the ventral neural tube. (C) Position of the transverse section shown in B. (D and E) In FoxA2–FoxA3 morphant, floor plate cells are elongated along the dorso-ventral axis of the neural tube, instead of being cuboidal. (F) Position of the area shown in E. (A and B) Transverse sections, dorsal up. (C–F) Lateral views, anterior to the left.

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Acknowledgments

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Reprinted from Developmental Biology, 350(2), Dal-Pra, S., Thisse, C., and Thisse, B., FoxA transcription factors are essential for the development of dorsal axial structures, 484-495, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.