ZFIN Image: Stickney et al., 2007, Fig. 2

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Fig. 2 Tail patterning is affected in bmp4 mutants. dlx3 (A ,B), flk1 (C, D), myod (E, F), pax2a (G, H), evx1 (I, J) and prdm1 (K, L) expression in 26 hpf wild-type (A, C, E, G, I, K) and bmp4^st72 mutant (B, D, F, H, J, L) embryos. Gaps in dlx3 and prdm1 expression in the tail fin (arrow) and reduction of staining in the cloacal region (arrowhead) are apparent in bmp4^st72 mutants (B, L). There is also a reduction in the extent of the flk1 expression domain in the tail of bmp4 mutants (D, bracket). Tail somites are fused across the ventral midline (F, arrowhead, inset) and the pronephric terminus is slightly altered in shape and location (H, arrowhead) in bmp4^st72 mutants. Expression of evx1 is reduced and more internal in bmp4^st72 mutants (J) than in wild-type embryos (I). All views are lateral with anterior to the left except the inset in panel F, which is a dorsal view.

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Acknowledgments

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Reprinted from Developmental Biology, 310(1), Stickney, H.L., Imai, Y., Draper, B., Moens, C. and Talbot, W.S., Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates, 71-84, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.