Fig. 8 Telencephalic progenitors express sox2 and have molecular characteristics of glia. (A–B) Comparison of BrdU incorporation (red) after 4 h tracing with the expression of sox2 (A–A″) or fabp7a (B) (blue, in situ hybridization). Cross-sections, dorsal up. Telencephalic progenitors are found in the expression domain of both markers. (C–E) Analysis in confocal microscopy (thickness 2 μm) of BLBP protein (green) and BrdU incoporation (red) after 4 h (C), 3 days (D) or 2 weeks (E). Examples of cells positive only for BrdU are indicated by red arrows, examples of cells doubly positive by yellow arrows. (F) Percentage of BLBP-positive cells that are also BrdU-positive after progressively longer tracing times. Note that this number strikingly decreases over time.
Reprinted from Developmental Biology, 295(1), Adolf, B., Chapouton, P., Lam, C.S., Topp, S., Tannhauser, B., Strähle, U., Gotz, M., and Bally-Cuif, L., Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon, 278-293, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.