ZFIN Image: Ramel et al., 2005, Fig. 2

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Figure Caption

Fig. 2 Wnt8 and BMP2b are necessary to repress anterior and posterior axial mesoderm and to maintain non-axial mesoderm. In situ hybridization for gsc (anterior axial mesoderm, A–E), myoD (adaxial mesoderm, F–J), and flh (posterior axial mesoderm, K–O) at bud stage. Genotypes are indicated above each column. Main panels A–E: lateral views, dorsal right. Insets: dorsal view, anterior up. F–O: dorsal views, anterior up. Insets: posterior view, dorsal up. Note that the slightly widened adaxial domain in swr mutants (G) and the progressive widening of the axial domain as wnt8 MO embryos have a reduced dosage of bmp2b (C–E, H–J, M–O).

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Acknowledgments

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Reprinted from Developmental Biology, 287(2), Ramel, M.C., Buckles, G.R., Baker, K.D., and Lekven, A.C., WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation, 237-248, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.