Gene

elavl4

ID

ZDB-GENE-990415-246

Name

ELAV like neuron-specific RNA binding protein 4

Symbol

elavl4 Nomenclature History

Previous Names

elrd (1)
elav-related D
wu:fc24h01
zHuD (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Involved in axonogenesis. Localizes to protein-containing complex. Is expressed in nervous system and trigeminal placode. Orthologous to human ELAVL4 (ELAV like RNA binding protein 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77361 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from Hao et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elavl4 Human Ortholog

No data available

Associated With elavl4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034918	HuD, RNA recognition motif 3
Family	IPR002343	Paraneoplastic encephalomyelitis antigen
Family	IPR006548	Splicing factor ELAV/Hu
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	HuD, RNA recognition motif 3	Nucleotide-binding alpha-beta plait domain superfamily	Paraneoplastic encephalomyelitis antigen	RNA-binding domain superfamily	RNA recognition motif domain	Splicing factor ELAV/Hu
UniProtKB:F1QGR7 InterPro	403
UniProtKB:A0A8M6Z808 InterPro	369
UniProtKB:A0A8M9QIF9 InterPro	395
UniProtKB:A0A8M9Q9I0 InterPro	398
UniProtKB:A0A0R4IEW8 InterPro	411
UniProtKB:A0A8M2BEA7 InterPro	382
UniProtKB:A0A8M9Q398 InterPro	408

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	elavl4-201 (1) Ensembl	Ensembl	2,109 nt	Select Tool
mRNA	elavl4-202 (1) Ensembl	Ensembl	1,818 nt	Select Tool
mRNA	elavl4-203 (1) Ensembl	Ensembl	797 nt	Select Tool
mRNA	elavl4-205 (1) Ensembl	Ensembl	6,093 nt	Select Tool ZFIN BLAST
mRNA	elavl4-206 (1) Ensembl	Ensembl	5,416 nt	Select Tool ZFIN BLAST
ncRNA	elavl4-006 (1) Ensembl	Ensembl	1,293 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-elavl	monoclonal	elavl3 elavl4	IgG2b	Mouse	IHC	Santa Cruz Biotechnology, Inc. Life Technologies (Invitrogen) Abcam plc MoBiTec Molecular Biotechnology Molecular Probes, Inc.	479

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations