Gene
pdgfab
- ID
- ZDB-GENE-060929-124
- Name
- platelet-derived growth factor alpha polypeptide b
- Symbol
- pdgfab Nomenclature History
- Previous Names
-
- wu:fc32c12
- zgc:153249
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have platelet-derived growth factor receptor binding activity. Predicted to be involved in several processes, including platelet-derived growth factor receptor signaling pathway; positive regulation of phosphatidylinositol 3-kinase signaling; and positive regulation of protein phosphorylation. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in malignant glioma. Is expressed in endoderm; mouth; pharyngeal arch; pharyngeal endoderm; and pharyngeal pouch. Orthologous to human PDGFA (platelet derived growth factor subunit A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Owen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived growth factor, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BAV6
|
207 | ||||
|
UniProtKB:Q08CD2
|
230 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
pdgfab-202
(1)
|
Ensembl | 876 nt | ||
| mRNA |
pdgfab-201
(1)
|
Ensembl | 2,286 nt | ||
| mRNA |
pdgfab-204
(1)
|
Ensembl | 1,181 nt | ||
| ncRNA |
pdgfab-004
(1)
|
Ensembl | 579 nt |
Interactions and Pathways
No data available
Plasmids
No data available