FIGURE

Fig. 2

ID
ZDB-FIG-220715-64
Publication
Owen et al., 2022 - Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis
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Fig. 2

Figure 2. Knockdown analysis of ventral retina and optic fissure specific genes in zebrafish. Confocal imaging of lateral views (dorsal up, anterior left) of immunofluorescence staining of laminin protein in zebrafish embryos at 76 hours post fertilization in (A) control MO or MO knockdowns of (B) ank3a, (C) ank3b, (D) bmpr1ba, (E) bmpr1bb, (F) bmpr1ba/bmpr1bb, (G) pdgfaa, (H) pdgfab, and (I) pdgfaa/pdgfab mutant embryos. Scale bar = 100 μm. MO, morpholino.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
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