Gene
tnr
- ID
- ZDB-GENE-030804-1
- Name
- tenascin R (restrictin, janusin)
- Symbol
- tnr Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Involved in axon guidance. Predicted to localize to collagen-containing extracellular matrix. Is expressed in brain; diencephalon; head; optic tectum; and retinal outer plexiform layer. Orthologous to human TNR (tenascin R).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Becker et al., 2003
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder, nonprogressive, with spasticity and transient opisthotonus | 619653 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020837 | Fibrinogen, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR041161 | Tenascin, EGF-like domain |
| Family | IPR050991 | Extracellular Matrix Regulatory Proteins |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | EGF-like domain | Extracellular Matrix Regulatory Proteins | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen, conserved site | Fibrinogen-like, C-terminal | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Tenascin, EGF-like domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T3T6
|
1350 | ||||||||||
|
UniProtKB:A0A8M2BIJ4
|
1261 |
Interactions and Pathways
No data available
Plasmids
No data available