FIGURE

Fig. 3

ID

ZDB-FIG-240506-59

Publication

Jayawardena et al., 2024 - Investigating the role of phenylalanine residues for amyloid formation of the neuropeptide neurokinin B

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Fig. 3

Formation of an intermolecular disulfide bond restores amyloid formation. Time-resolved ThT fluorescence shows NKB(F6C) forms few fibrils when in reducing conditions (NKB(F6C), R), but when in non-reducing conditions, (NKB(F6C), NR), ThT-positive fibrils are generated. Fibril formation by wild-type NKB (NKB(WT) is shown for comparison. Peptides were 200 μM in 10 mM nEM, pH 7.4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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