FIGURE

Fig. 4

ID

ZDB-FIG-240425-25

Publication

Iglesias Gonzalez et al., 2024 - Perturbed development of calb2b expressing dI6 interneurons and motor neurons underlies locomotor defects observed in calretinin knock-down zebrafish larvae

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Fig. 4

Calretinin deficient larvae displayed a reduced amount of dmrt3aRFP cells. A) Brightfield images of calb2a, calb2b double morphants versus controls at 3 days post fertilization (dpf). B) Confocal images of immunohistochemistry against calretinin in controls and calretinin knock-down larvae. C) Confocal images showing dmrt3aRFP transgenic line in control and calretinin knock-down larvae at 3 dpf. D) Confocal images showing dmrt3aRFP transgenic line in control and calretinin knock-down larvae at 6 dpf. Arrowheads indicate CoLo axons. E) Quantification of dmrt3aRFP at 3 dpf. F) Quantification of dmrt3aRFP at 6 dpf. Scale bar, 50 μm. Statistical differences: >0.05 (ns), ≤0.05 (*), ≤0.01 (**), ≤0.001 (***) and ≤0.0001 (****).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Developmental Biology, 508, Iglesias Gonzalez, A.B., Koning, H.K., Tuz-Sasik, M.U., van Osselen, I., Manuel, R., Boije, H., Perturbed development of calb2b expressing dI6 interneurons and motor neurons underlies locomotor defects observed in calretinin knock-down zebrafish larvae, 778777-87, Copyright (2024) with permission from Elsevier. Full text @ Dev. Biol.