Figure 8

Percent distribution of DEPs. Distribution of differentially regulated proteins among functional categories. Left Panel Proteins downregulated in vtg2-mutant offspring (upregulated in Wt, N = 83). Right Panel Proteins upregulated in vtg2-mutant offspring (N = 176). Only proteins that were identified in > 4 biological samples and that exhibited a ≥ 1.0-fold difference in N-SC between groups (vtg2-mutant versus Wt), or proteins unique to a certain group, were included in this analysis. The overall distribution of differentially regulated proteins among the functional categories significantly differed between mutant and Wt eggs (χ2, p < 0.05). Asterisks indicate significant differences between different groups in the proportion of differentially regulated proteins within a functional category (χ2, p < 0.05). The corresponding Ensembl Protein IDs and associated gene, transcript and protein names, functional categories (shown above), regulation (upregulated or downregulated in mutant compared to Wt), and fold-difference in N-SC between vtg2-mutant and Wt eggs for proteins included in this analysis are given in S1 Table.