FIGURE

Fig. 3

ID

ZDB-FIG-231004-37

Publication

Fontana et al., 2023 - adgrl3.1-deficient zebrafish show noradrenaline-mediated externalizing behaviors, and altered expression of externalizing disorder-candidate genes, suggesting functional targets for treatment

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Fig. 3

RNA-seq summary data.

A Principal component analysis plot of the top 200 most variable genes after differential expression analysis. n = 4 brains/group. B Venn diagram showing the overlap of differentially expressed genes (DEGs) between WT zebrafish, adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. C Heatmap of DEGs (lowest adjusted p value (p_adj) < 0.05 and LFC > |2 | ) between WT and adgrl3.1^−/−. D Volcano plot displaying DEGs between WT and adgrl3.1^−/−. DEGs with p_adj are highlighted. n = 4 per group. E Heatmap of DEGs (p_adj < 0.05 and LFC > |2 | ) between WT and adgrl3.1^−/− treated with atomoxetine. F Volcano plot displaying DEGs between WT and adgrl3.1^−/− treated with atomoxetine. DEGs with p_adj are highlighted. n = 4 per group. G Heatmap of DEGs (p_adj < 0.05 and LFC > |2 | ) between adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. H Volcano plot displaying DEGs between adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. DEGs with p_adj are highlighted. n = 4 per group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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