Fig. 3

Fig. 3 RNA-seq summary data.

A Principal component analysis plot of the top 200 most variable genes after differential expression analysis. n = 4 brains/group. B Venn diagram showing the overlap of differentially expressed genes (DEGs) between WT zebrafish, adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. C Heatmap of DEGs (lowest adjusted p value (p_adj) < 0.05 and LFC > |2 | ) between WT and adgrl3.1^−/−. D Volcano plot displaying DEGs between WT and adgrl3.1^−/−. DEGs with p_adj are highlighted. n = 4 per group. E Heatmap of DEGs (p_adj < 0.05 and LFC > |2 | ) between WT and adgrl3.1^−/− treated with atomoxetine. F Volcano plot displaying DEGs between WT and adgrl3.1^−/− treated with atomoxetine. DEGs with p_adj are highlighted. n = 4 per group. G Heatmap of DEGs (p_adj < 0.05 and LFC > |2 | ) between adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. H Volcano plot displaying DEGs between adgrl3.1^−/− and adgrl3.1^−/− treated with atomoxetine. DEGs with p_adj are highlighted. n = 4 per group.