FIGURE
Fig. 10
- ID
- ZDB-FIG-230829-28
- Publication
- George et al., 2022 - Zebrafish model of RERE syndrome recapitulates key ophthalmic defects that are rescued by small molecule inhibitor of shh signaling
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Fig. 10
Human RERE variants exhibit hypomorphic activity in vivo and mis-localized expression in vitro. In vivo assay to determine the efficiency of human RERE variants (80 pg) to cause cyclopia in zebrafish model (A, χ2 test was used to determine level of significance and “*” denotes significant difference). In vitro assay to determine the nuclear localization pattern of human RERE wild type (WT, B) and mutant proteins (C) in HEK293 cells. Scale bar is 10 μm.
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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