FIGURE

Figure 7

ID

ZDB-FIG-230828-88

Publication

Dalla Barba et al., 2023 - Modeling Sarcoglycanopathy in Danio rerio

Other Figures

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Figure 7

Muscle fiber integrity in the representative wild type and sgcd^−/− larvae growing in fish water with 1% methylcellulose added. (A) Representative birefringence images as obtained by viewing zebrafish with a plane polarizing filter. Microscope’s magnification 2.5X. (B) Birefringence quantification of zebrafish larvae as in (A) (wild type N = 39; sgcd^−/− N = 45). (C) Representative pictures of the phalloidin staining of whole zebrafish larvae at 5 dpf. Microscope’s magnification 20X. (D) Quantification of the fluorescence intensity of zebrafish larvae stained with phalloidin as in (B) (wild type N = 7; sgcd^−/− N = 11). Statistical analysis was performed by the Mann–Whitney test; ****, p ≤ 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sgcd^ia401/ia401
Condition:	chemical treatment by environment: methyl cellulose
Observed In:	myotome skeletal muscle cell skeletal muscle cell myoseptum skeletal muscle cell sarcomere
Stage:	Day 5

Phenotype Detail

Acknowledgments

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