FIGURE

Figure 6

ID

ZDB-FIG-230609-15

Publication

Grabinski et al., 2023 - Comparative analysis of transcriptional changes in zebrafish cep290 and bbs2 mutants by RNA-seq reveals upregulation of inflammatory and stress-related pathways

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Figure 6

cep290 and bbs2 mutant gene expression as compared to a regeneration time series. (A) Differentially expressed genes across a 28-day retinal regeneration versus expression in cep290 and bbs2 versus wild-type. Expression in the mutants did not reach the levels seen between 24 h post-lesion and 5 days post-lesion and was most comparable to animals 10–28 days post-lesion. (B) 179 of the DEGs shared between cep290 and bbs2 were also differentially expressed between 24 and 72 h post-lesion, and the expression of these genes closely paralleled that of the actively regenerating animals.

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.