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Figure 2

ID

ZDB-FIG-230609-11

Publication

Grabinski et al., 2023 - Comparative analysis of transcriptional changes in zebrafish cep290 and bbs2 mutants by RNA-seq reveals upregulation of inflammatory and stress-related pathways

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Figure 2

Enrichment of differentially expressed genes in biological processes of interest in cep290 and bbs2 mutants. (A) Log/log plot of DEG fold changes of common DEGs in cep290^−/− and bbs2^−/− datasets. Blue circles represent downregulated DEGs. Red circles represent common upregulated DEGs. Purple circles are DEGs upregulated in bbs2^−/− retina but downregulated in cep290^−/− retinas. Green circles are DEGs downregulated in bbs2^−/− retinas but upregulated in cep290^−/− retinas. (B) Heat map of the log₂ fold change in the top 50 most abundantly expressed of the 815 DEGs in common by read count. Most DEGs were downregulated. (C) Heat map of the log₂ fold change in the top 50 DEGs with greatest fold change in expression.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.