FIGURE

Figure 1

ID

ZDB-FIG-230529-50

Publication

MacLean et al., 2023 - phox2ba: The Potential Genetic Link behind the Overlap in the Symptomatology between CHARGE and Central Congenital Hypoventilation Syndromes

Other Figures

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Figure 1

phox2ba expression is reduced in chd7 mutants compared to sibling embryos. (A) Representative images of chd7^+/− cross embryos stained for phox2ba at 48 h post−fertilization (hpf) with scored phenotypes. Note that there are variable levels of expression ranging from “low” = 1, “medium” = 2, and “high” = 3. (B) Phenotype fractions bar graph of phox2ba staining in (A). Staining patterns were quantified by scoring based on intensity. The numbers of embryos scored for each genotype are indicated above the graphs. Note the increased proportion of embryos with weak staining patterns in the chd7^−/− group. (Chi-square p = 0.0363 (indicated by ‘*’ above the mutant bar).

Expression Data

Gene:	phox2ba
Fish:	TU chd7^hsi3/hsi3 (TU) chd7^hsi3/+ (TU)
Anatomical Term:	head
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chd7^hsi3/hsi3 (TU)
Observed In:	head
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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