FIGURE

Figure 2.

ID

ZDB-FIG-230419-2

Publication

Leyhr et al., 2022 - A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint

Other Figures

All Figure Page

Back to All Figure Page

Figure 2.

A conserved non-coding element, jaw joint regulatory sequence 1 (JRS1), identified using mVISTA and MEME.

(A) mVISTA alignment of vertebrate Nkx3.2 loci, using the spotted gar locus as reference. Peaks indicate conserved sequences >50% identity, coloured peaks indicate >70% identity. Dark blue peaks indicate conserved exon sequences, pink indicates conserved non-coding sequences. (B) Shared sequence motifs (1–4) in the core ~245 bp sequence of JRS1 in different species identified with MEME analysis. p values indicated per species (horizontal) and per motif (vertical). (C) Relevant transcription factor-binding sites predicted by Tomtom at motifs 1–4 with associated p values for each match.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife