FIGURE
Figure 8.
- ID
- ZDB-FIG-221119-19
- Publication
- Leyhr et al., 2022 - A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint
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Figure 8.
Graphical summary of this study.The conserved jaw joint regulatory sequence 1 (JRS1) enhancer was first identified as a conserved non-coding element (CNE) in silico, then confirmed with transgenesis experiments of a range of species-specific JRS1 sequences driving fluorescent reporter expression in the jaw joint. Finally, the JRS1 enhancer was deleted from the zebrafish genome to reveal a transient jaw joint dysmorphology and partial fusion. m: Meckel’s cartilage; pq: palatoquadrate; ra: retroarticular process. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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