FIGURE

FIGURE 4

ID

ZDB-FIG-230331-55

Publication

Raterman et al., 2023 - Disruption of the foxe1 gene in zebrafish reveals conserved functions in development of the craniofacial skeleton and the thyroid

Other Figures

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FIGURE 4

The foxe1 ^rdb2 mutant. (A) Wild type and foxe1 ^rdb2 mutant DNA sequence at (C) 84–105. The protospacer adjacent motif is underlined (full gRNA sequence: 5′-GCCGCAAAGAGGCCGTCGGAGG-3′). The deletion is highlighted in red and the insertion in green. (B) Schematic representation of the zebrafish Foxe1 protein and the position of the amino acid changes as indicated by the red bars. (C) Nuclear localization of wild type Foxe1 and cytoplasmatic localization of mutant Foxe1 in zebrafish keratinocytes on scale. Scale bar 50 µm. (D) Representative images of wild types and foxe1 mutants at 6 dpf and 2 months post fertilization. Scale bars 1 mm.

Expression Data

Gene:	foxe1
Antibody:	Ab1-foxe1
Fish:	AB foxe1^rdb2/rdb2 (AB)
Anatomical Terms:	keratinocyte cytoplasm keratinocyte nucleus
Stage:	Days 45-89

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxe1^rdb2/rdb2 (AB)
Observed In:	keratinocyte cytoplasm whole organism
Stage Range:	Day 6 to Days 45-89

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol