FIGURE 1
- ID
- ZDB-FIG-230331-52
- Publication
- Raterman et al., 2023 - Disruption of the foxe1 gene in zebrafish reveals conserved functions in development of the craniofacial skeleton and the thyroid
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Foxe1 protein structure in human, mouse and zebrafish. Multiple sequence alignment of full-length human, mouse and zebrafish FOXE1 protein. The protein contains three characterized domains which are annotated with colored lines. The similarity of the Forkhead domain (FHD) is 97% and 100%, respectively, between zebrafish and humans and between mouse and human. The sequence similarity of the whole protein between human and zebrafish is 54%. NLS is 100% identical between all species and the poly alanine stretch (PAS) is only present in humans and mouse. Red boxes mark the putative DNA-binding residues and asterisks (*) mark locations of missense mutations that were reported in individuals with Bamforth–Lazarus syndrome ( |