FIGURE

Fig. 3

ID

ZDB-FIG-230317-6

Publication

Smith et al., 2021 - Lysosomes and the pathogenesis of merosin-deficient congenital muscular dystrophy

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Fig. 3

Lysosome distribution in immobilized caf mutants. (A–B) Lysosome distribution in BTS-immobilized WT and caf embryos is similar; lysosomes do not redistribute to the myosepta in paralyzed caf mutants. White arrows indicate the side of the fiber attached to the myosepta. (C) Lamp1-RFP fluorescence intensity at the myosepta was not significantly different in immobilized caf mutants at 4 dpf (P = 0.2591, n = 36 fibers) compared with WT. Bars represent mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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