FIGURE

Fig 5

ID
ZDB-FIG-221216-72
Publication
Liu et al., 2022 - LOF variants identifying candidate genes of laterality defects patients with congenital heart disease
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Fig 5

Candidate genes are required for KV formation and ciliogenesis.

(A) The light-micro graph at the 8-somite stage showed different KV sizes, including normal and small. (B) The vesicle size of KV apical area. N≥19. (C) Fluorescent immunostaining of cilia in KV using anti-α-Tubulin antibodies at the 12hpf. (D) LRO Cilia number per KV was quantified and the group values were expressed as the mean ± SD. N≥15. (E) The average length of LRO Cilia per KV was quantified and the group values were expressed as the mean ± SD. N≥7. (F) The ciliary beat frequency (CBF). N≥12. Statistical significance was determined by Mann Whitney test; *P <0.05, ***P < 0.001, respectively vs. Std.

Expression Data
Antibody:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: 5-9 somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: 5-9 somites

Phenotype Detail
Acknowledgments
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