Fig. 4

a Normalized expression of TTLL11 in healthy tissues and the corresponding primary tumor samples across 13 different cancer types, separately and combined (PANCAN). Nominal P values: ****P ≤ 0.0001; ***P ≤ 0.001; **P ≤ 0.01; *P ≤ 0.05; based on unmatched two-sided Wilcoxon rank-sum tests. The number of samples per cancer type and sample type (see Supplementary Table 3). In each box plot, the median value is indicated as a horizontal line and the lower and upper bounds of the box correspond to the first- and third quartiles, respectively. The upper- and lower whiskers range from the corresponding box hinges to the largest value no further than 1.5 times the interquartile range from the hinge. All outlying data points beyond the whiskers are plotted individually. b Spearman correlation coefficients of normalized gene expression and sample aneuploidy scores for every gene across 13 different cancer types. PANCAN represents the median correlation coefficient for every gene across cancers. TTLL11 is highlighted in red. Nominal P values: *P ≤ 0.05, based on one-sided, one-sample Z tests. The number of genes detected per cancer type (see Supplementary Table 4). In each box plot, the median value is indicated as a horizontal line and the lower and upper bounds of the box correspond to the first and third quartiles, respectively. The upper- and lower whiskers range from the corresponding box hinges to the largest value no further than 1.5 times the interquartile range from the hinge. All outlying data points beyond the whiskers are plotted individually.