FIGURE

Figure 5

ID

ZDB-FIG-221118-80

Publication

Almohaisen et al., 2022 - B cell lymphoma 6A regulates immune development and function in zebrafish

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Figure 5

Analysis of macrophage migration in response to injury in bcl6aa mutant zebrafish. (A) Wounding assay on 4 dpf embryos subjected to injury via tail fin transection, showing fluorescence images of representative bcl6aa^wt/wt (wt/wt), bcl6aa^wt/mdu21 (wt/mdu21) and bcl6aa^mdu21/mdu21 (mdu21/mdu21) embryos on the Tg(mpeg1.1:GFP) background, as determined by retrospective genotyping, at the times indicated, with the dotted line showing the wounding site. Scale bars represent 200 μm. (B) Quantitation of the total number of GFP+ macrophage migrated at the indicated timepoint showing mean ± SEM. (***p<0.001; n>20 mixed progeny). (C) Cumulative proportion of embryos with at least 1 GFP+ cell migrated assessed at 0.25 h intervals (n>20).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT bcl6aa^mdu21/mdu21 bcl6aa^mdu21/+
Condition:	transection: caudal fin
Observed In:	caudal fin macrophage migration
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Infect Microbiol