FIGURE

Fig. 5

ID

ZDB-FIG-220905-21

Publication

Waldmann et al., 2021 - The role of Gdf5 in the development of the zebrafish fin endoskeleton

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Fig. 5

Median fin histology of adult wild-type and gdf5^{uu3703/uu3703} zebrafish reveals intact joints between distal and proximal radials and normal maturation of the skeletal elements. Sagittal sections from 60 dpf of wild-type (A,A,C,C′,E,E′) and gdf5^{uu3703/uu3703} (B,B′,D,D′,F,F′) zebrafish median fins stained with Hematoxylin and Eosin (HE). Anterior to the left, dorsal to the top. Dashed boxes in A-F mark magnified region in A′-F′. (A,A′,B,B′) Dorsal fin; (C,C′,D,D′) anal fin; (E,E′,F,F′) caudal fin. (A′-D′) White arrowheads indicate joint capsule, black arrowheads indicate articular cartilage. All joints are intact and do not display any differences when compared to wild-type. (E-F,E′-F′) Caudal fin skeletal elements display no apparent delay in chondrocyte maturation when compared to wild-type. Scale bars: 500 μm (A-F), 100 μm (A′-F′)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gdf5^{uu3703/uu3703} (AB)
Observed In:	anal fin chondrocyte development anal fin distal radial joint anal fin proximal radial joint caudal fin chondrocyte development dorsal fin chondrocyte development dorsal fin distal radial joint dorsal fin proximal radial joint
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

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