FIGURE

Fig. 4

ID

ZDB-FIG-220819-14

Publication

Wu et al., 2022 - dock8 deficiency attenuates microglia colonization in early zebrafish larvae

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Fig. 4

A Schematic diagram of the imaging region. Black dash lines represent the imaging area. B Quantification of migration speed of mpeg1⁺ cells in dock8^-15,+5bp mutants and siblings yolk sac within 4 h from 3 dpf, each dot represents one larva. C Representative images of mpeg1⁺ cells tracking in dock8^-15,+5bp mutants and siblings yolk sac at 3 dpf. Each line represents the migration path of one macrophage. D Time-lapse confocal imaging of Tg(mpeg1:DsRed);dock8^15,+5bp embryos from 3 dpf within 4 h. Each line represents the migration path of one macrophage. White dotted lines indicate the yolk sac. Scale bar = 100 µm. See also Video S 1. Data were analyzed by unpaired Student’s t-tests. ^**P ≤ 0.01.

Expression Data

Gene:	DsRedx
Fish:	hkz15Tg (AB) dock8^szy104/+; hkz15Tg (AB) dock8^{szy104/szy104}; hkz15Tg (AB)
Anatomical Term:	yolk macrophage
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hkz15Tg (AB) dock8^szy104/+; hkz15Tg (AB) dock8^{szy104/szy104}; hkz15Tg (AB)
Observed In:	yolk macrophage migration
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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