FIGURE

Fig. 2

ID

ZDB-FIG-220819-12

Publication

Wu et al., 2022 - dock8 deficiency attenuates microglia colonization in early zebrafish larvae

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Fig. 2

A Schematic diagram of the imaging region. Black dash lines represent the imaging area. B, E, H Representative images (B) and quantification of 4 dpf (E) and 6 dpf (H) NR signals of dock8^-15,+5bp mutants and siblings. C, F, I Representative images (C) and quantification of 4 dpf (F) and 6 dpf (I) apoeb WISH signals of dock8^-15,+5bp mutants and siblings. D, G, J Representative images (D) and quantification of 4 dpf (G) and 6 dpf (J) mpeg1-dsredx positive cells in optic tectum of dock8^-15,+5bp mutants and siblings. Group sizes were at least n = 30 zebrafish embryos. Each dot represents one larva. White dashed lines indicate the optic tectum. Scale bar = 100 µm. Data were analyzed by unpaired Student’s t-tests. ^nsP > 0.05;^****P ≤ 0.0001.

Expression Data

Genes:	apoeb DsRedx
Fish:	hkz15Tg (AB) dock8^szy104/+; hkz15Tg (AB) dock8^{szy104/szy104}; hkz15Tg (AB)
Anatomical Term:	optic tectum microglial cell
Stage Range:	Day 4 to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hkz15Tg (AB) dock8^szy104/+; hkz15Tg (AB) dock8^{szy104/szy104}; hkz15Tg (AB)
Observed In:	microglial cell lysosome optic tectum microglial cell
Stage Range:	Day 4 to Day 6

Phenotype Detail

Acknowledgments

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