FIGURE
Fig. 4
- ID
- ZDB-FIG-220630-39
- Publication
- Reurink et al., 2022 - Scrutinizing pathogenicity of the USH2A c.2276 G > T; p.(Cys759Phe) variant
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Fig. 4
Rhodopsin localization to the photoreceptor cell body in the ush2ap.(Cys771Phe) zebrafish.
a Rhodopsin (green signal) localizes to the rod photoreceptor outer segments in wildtype larval eyes. A visual representation of a photoreceptor is shown on the right. b Aberrant localization of rhodopsin to the photoreceptor cell body was observed in ush2ap.(Cys771Phe) larvae (indicated by white arrows), which was observed in a significantly higher number of photoreceptors of ush2ap.(Cys771Phe) larvae as compared to wildtype larvae (c; unpaired t test). Nuclei are stained with DAPI (blue signal). Scale bar: 10 µM. ****p < 0.0001. |
Expression Data
| Antibody: | |
|---|---|
| Fish: | |
| Anatomical Terms: | |
| Stage: | Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
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| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
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Full text @ NPJ Genom Med