FIGURE

Figure 1

ID

ZDB-FIG-220518-39

Publication

Longhitano et al., 2022 - Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma

Other Figures

All Figure Page

Back to All Figure Page

Figure 1

Lactate and 3,5-dihydroxybenzoic acid (3,5-DHBA) promoted glioblastoma cell proliferation and migration. (A–C) Real-time cell proliferation monitoring in U-87 MG cells (A), A-172 cells (B), and U-251 cells (C) using the xCELLigence system following treatments with lactate (20 mM) and 3,5-DHBA (150 μM). The cell index values were normalized at the time of pharmacological treatments in order to obtain a normalized cell index. Each line expresses the average of four different experiments. (E–G) Analysis of human glioblastoma cell migration in U-87 MG cells (E), A-172 cells (D–F), and U-251 MG cells (G) with the wound healing assay following treatments with lactate (20 mM) and 3,5-DHBA (150 μM). The figures presented are representative of at least three independent experiments (mean ± SEM). P-values <0.05 were considered as statistically significant (*p < 0.05; ***p < 0.001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Oncol