FIGURE

Figure 1

ID
ZDB-FIG-220430-67
Publication
Doretto et al., 2022 - Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners
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Figure 1

Figure 1. GFR?1 predicted amino acid sequence alignment. Numbers at the top left of the sequences indicate amino acid positions, dashes indicate deletions and black boxes indicate shared sequences. The three cysteine-rich domains (D1?D3) (orange lines), 28 cysteine residues (*) (plus 2 in the terminal region) and two triplets (MLF and RRR) (green boxes) are highly conserved among humans, rodents and zebrafish. At the end of the alignment are the percentage identity values of zebrafish Gfr?1a and Gfr?1b in relation to the other corresponding sequences. The blue line indicates the amino acid sequence recognized by the zebrafish Gfr?1a antibody used in this study; the purple line indicates the putative motifs critical for binding to GDNF.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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