FIGURE

Fig. 8

ID

ZDB-FIG-220127-10

Publication

Nord et al., 2021 - Genetic compensation between Pax3 and Pax7 in zebrafish appendicular muscle formation

Other Figures

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Fig. 8

Initiation of muscle regeneration is not affected by the absence of pax7 and pax3. Transgenic expression of Pax3a:GFP (green) and incorporation of BrdU (red) in A-F wt (n = 16), G-L, pax7a−/−/7b−/− double mutant (n = 15) and, M-R, pax3a−/−/7a−/−/7b−/− triple mutant (n = 13) zebrafish embryos injured at somite number 10 at 4 dpf shown at A,D,G,J,M,P 1 dpi, B,E,H,K,N,Q, 2 dpi, and, C,F,I,L,O,R, 3 dpi. Average number of Pax3a:GFP+, BrdU+ and Pax3:GFP/BrdU double positive cells per somite at 1, 2, and 3 dpi is presented in S-U. Error bars indicate SEM and significance was calculated using Student's t-test where P < .05 was considered significant. Arrowheads indicate area of injury. Scale bar: 100 μm

Expression Data

Gene:	EGFP
Fish:	i150Tg pax7a^umu3/umu3; pax7b^umu4/umu4; i150Tg pax7a^umu3/umu3; pax3a^umu5/umu5; pax7b^umu4/umu4; i150Tg
Condition:	perforation: somite 10
Anatomical Term:	myotome
Stage Range:	Day 5 to Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	i150Tg pax7a^umu3/umu3; pax7b^umu4/umu4; i150Tg pax7a^umu3/umu3; pax3a^umu5/umu5; pax7b^umu4/umu4; i150Tg
Condition:	perforation: somite 10
Observed In:	myotome somite 10 skeletal muscle tissue regeneration
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

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