FIGURE

FIGURE 3

ID

ZDB-FIG-211111-22

Publication

Qiang et al., 2021 - Fibroblast Growth Factor 21 Augments Autophagy and Reduces Apoptosis in Damaged Liver to Improve Tissue Regeneration in Zebrafish

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FIGURE 3

Fibroblast growth factor 21 reduces oxidative stress after liver injury. Samples were collected at 0, 24, and 48 hpa to assess oxidative stress in the damaged liver. (A) Evaluation of SOD activity in the control and differentially treated embryos. (B) Evaluation of CAT activity in the control and differentially treated embryos. (C) Evaluation of MDA content in the control and differentially treated embryos. (D) Evaluation of AST activity in the control and differentially treated embryos. (E) Evaluation of ALT activity in the control and differentially treated embryos. DMSO group: without Mtz treatment, DMSO was applied. Mtz group: after Mtz treatment, grow naturally. Mtz+FGF21 group: after Mtz treatment, treated with FGF21 standard protein. Significance: *p< 0.05, **p< 0.01, and ***p< 0.001 vs. DMSO group. Data are expressed as mean ± SEM (n = 40 per group, repeat 3 times for each test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cq1Tg
Condition:	chemical treatment by environment: metronidazole
Observed In:	catalase activity liver malonaldehyde superoxide dismutase activity
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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